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The following term was not found in PubMed: ENSG00000120727
Page 1
Polyadenylate-binding protein-interacting proteins PAIP1 and PAIP2 affect translation termination.
Ivanov A, Shuvalova E, Egorova T, Shuvalov A, Sokolova E, Bizyaev N, Shatsky I, Terenin I, Alkalaeva E. Ivanov A, et al. J Biol Chem. 2019 May 24;294(21):8630-8639. doi: 10.1074/jbc.RA118.006856. Epub 2019 Apr 16. J Biol Chem. 2019. PMID: 30992367 Free PMC article.
Additionally, two other proteins, poly(A)-binding protein-interacting proteins 1 and 2 (PAIP1 and PAIP2), bind the same domain of PABP and regulate its translation-related activity. ...Moreover, PAIP1 and PAIP2 inhibited the activity of free PABP on translation term …
Additionally, two other proteins, poly(A)-binding protein-interacting proteins 1 and 2 (PAIP1 and PAIP2), bind the same domain of PAB …
PAIP2 is a potential diagnostic and prognostic biomarker of breast cancer and is associated with immune infiltration.
Wang C, Jiang X, Qi J, Xu J, Yang G, Mi C. Wang C, et al. Front Genet. 2022 Nov 10;13:1009056. doi: 10.3389/fgene.2022.1009056. eCollection 2022. Front Genet. 2022. PMID: 36437922 Free PMC article.
However, the possible role of PAIP2 in the progression of breast cancer is still unknown. RT-qRCR and Western blotting were used to verify the expression of PAIP2 in breast cancer cells and normal breast cells. ...Our study explored the potential value of PAIP2
However, the possible role of PAIP2 in the progression of breast cancer is still unknown. RT-qRCR and Western blotting were used to v …
Paip2 is localized to active promoters and loaded onto nascent mRNA in Drosophila.
Kachaev ZM, Lebedeva LA, Kozlov EN, Toropygin IY, Schedl P, Shidlovskii YV. Kachaev ZM, et al. Cell Cycle. 2018;17(14):1708-1720. doi: 10.1080/15384101.2018.1496738. Epub 2018 Aug 1. Cell Cycle. 2018. PMID: 29995569 Free PMC article.
Paip2 (Poly(A)-binding protein - interacting protein 2) is a conserved metazoan-specific protein that has been implicated in regulating the translation and stability of mRNAs. ...Nuclear Paip2 is associated with chromatin, and in chromatin immunoprecipitation experi
Paip2 (Poly(A)-binding protein - interacting protein 2) is a conserved metazoan-specific protein that has been implicated in regulati
Paip2 cooperates with Cbp80 at an active promoter and participates in RNA Polymerase II phosphorylation in Drosophila.
Kachaev ZM, Lebedeva LA, Shaposhnikov AV, Moresco JJ, Yates JR 3rd, Schedl P, Shidlovskii YV. Kachaev ZM, et al. FEBS Lett. 2019 May;593(10):1102-1112. doi: 10.1002/1873-3468.13391. Epub 2019 Apr 29. FEBS Lett. 2019. PMID: 31001806 Free PMC article.
The Paip2 protein is a factor regulating mRNA translation and stability in the cytoplasm. It has also been found in the nuclei of several cell types in Drosophila. Here, we aim to elucidate the functions of Paip2 in the cell nucleus. We find that nuclear Paip2
The Paip2 protein is a factor regulating mRNA translation and stability in the cytoplasm. It has also been found in the nuclei of sev …
Poly(A)-binding protein-interacting protein 2, a strong regulator of vascular endothelial growth factor mRNA.
Onesto C, Berra E, Grépin R, Pagès G. Onesto C, et al. J Biol Chem. 2004 Aug 13;279(33):34217-26. doi: 10.1074/jbc.M400219200. Epub 2004 Jun 2. J Biol Chem. 2004. PMID: 15175342 Free article.
Using an in vitro RNA degradation assay, the half-life of VEGF 3'-UTR was found to be increased by overexpressing PAIP2. PAIP2 stabilizes endogenous VEGF mRNA in Tet-on cells, leading to increased VEGF secretion. Moreover, RNAi-mediated knock-down of PAIP2 si …
Using an in vitro RNA degradation assay, the half-life of VEGF 3'-UTR was found to be increased by overexpressing PAIP2. PAIP2
A combination of multiple autoantibodies is associated with the risk of Alzheimer's disease and cognitive impairment.
Shim SM, Koh YH, Kim JH, Jeon JP. Shim SM, et al. Sci Rep. 2022 Jan 25;12(1):1312. doi: 10.1038/s41598-021-04556-2. Sci Rep. 2022. PMID: 35079008 Free PMC article.
The serum levels of four autoantibodies including anti-ATCAY, HIST1H3F, NME7 and PAIP2 IgG were significantly different among NC, MCI and/or AD groups. ...This study indicates that anti-ATCAY and anti-PAIP2 autoantibodies could be a potential diagnostic biomarker of …
The serum levels of four autoantibodies including anti-ATCAY, HIST1H3F, NME7 and PAIP2 IgG were significantly different among NC, MCI …
Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2.
Yoshida M, Yoshida K, Kozlov G, Lim NS, De Crescenzo G, Pang Z, Berlanga JJ, Kahvejian A, Gehring K, Wing SS, Sonenberg N. Yoshida M, et al. EMBO J. 2006 May 3;25(9):1934-44. doi: 10.1038/sj.emboj.7601079. Epub 2006 Apr 6. EMBO J. 2006. PMID: 16601676 Free PMC article.
PABP depletion by RNA interference (RNAi) causes co-depletion of Paip2 protein without affecting Paip2 mRNA levels. Upon PABP knockdown, Paip2 interacts with EDD, which leads to Paip2 ubiquitination. Supporting a critical role for EDD in Paip2 d …
PABP depletion by RNA interference (RNAi) causes co-depletion of Paip2 protein without affecting Paip2 mRNA levels. Upon PABP …
A new role for the cellular PABP repressor Paip2 as an innate restriction factor capable of limiting productive cytomegalovirus replication.
McKinney C, Yu D, Mohr I. McKinney C, et al. Genes Dev. 2013 Aug 15;27(16):1809-20. doi: 10.1101/gad.221341.113. Genes Dev. 2013. PMID: 23964095 Free PMC article.
Coordinate control of PABP1, Paip2, and EDD1 required the virus-encoded UL38 mTORC1 activator and resulted in augmented Paip2 synthesis, stability, and association with PABP1. ...Significantly, Paip2 accumulation was dependent on PABP accrual, as preventing P …
Coordinate control of PABP1, Paip2, and EDD1 required the virus-encoded UL38 mTORC1 activator and resulted in augmented Paip2
Dual interactions of the translational repressor Paip2 with poly(A) binding protein.
Khaleghpour K, Kahvejian A, De Crescenzo G, Roy G, Svitkin YV, Imataka H, O'Connor-McCourt M, Sonenberg N. Khaleghpour K, et al. Mol Cell Biol. 2001 Aug;21(15):5200-13. doi: 10.1128/MCB.21.15.5200-5213.2001. Mol Cell Biol. 2001. PMID: 11438674 Free PMC article.
Here we studied the Paip2-PABP interaction. Biacore data and far-Western analysis revealed that Paip2 contains two binding sites for PABP, one encompassing a 16-amino-acid stretch located in the C terminus and a second encompassing a larger central region. ...Thus, …
Here we studied the Paip2-PABP interaction. Biacore data and far-Western analysis revealed that Paip2 contains two binding sit …
Suppression of cellular transformation by poly (A) binding protein interacting protein 2 (Paip2).
Rosenfeld AB. Rosenfeld AB. PLoS One. 2011;6(9):e25116. doi: 10.1371/journal.pone.0025116. Epub 2011 Sep 21. PLoS One. 2011. PMID: 21957478 Free PMC article.
The ability of Paip2 to bind to Pabp is required to suppress the transformed phenotype mediated by hRas(V12). These observations indicate that Paip2 is able to function as a tumor suppressor....
The ability of Paip2 to bind to Pabp is required to suppress the transformed phenotype mediated by hRas(V12). These observations indi …
62 results